College football is back and week 12 once again saw a shake up in the AP rankings. Our experts preview the hottest games of the week and give their picks based on the BetQL computer simulation model. Check out our expert college football picks for week 13.
The Trojans are still in the mic to make the CFP, but they'll need to win this week to do it. After three straight conference wins, USC is master of their own destiny. A win against the Ducks this week and finishing out the season with a win over UCLA probably wouldn't be enough to get USC to the Big 10 title game, but it would improve their ranking to get them into the CFP, knocking Oregon out in the process. The Trojans are top 10 in passing and scoring this season, outscoring their opponents by nearly 17 points per game on average. As for Oregon, right now they have the 7th seed in the CFP bracket, and as previously mentioned would need to win on Saturday to keep their playoff spot. Oregon is top 10 in rushing, points scored and points allowed per game, but have only a 12% chance of making the Big 10 title game.
The BetQL computer model has the Ducks winning in 84% of its simulations with a projected final score of 35- 22.5. DraftKings has the spread currently at 9.5. Our tip take Oregon -9.5 currently at -112.
Check out our full game analysis here.

A win for the Yellow Jackets would mean a guaranteed spot in the ACC championship game regardless of what happens next week against Georgia. The ACC champion is guaranteed the #11 spot and right now Georgia Tech is in the driver's seat. If they were able to win out and crack the top 10, which a win over Georgia would almost certainly do for them, they'd be set. As for Pitt, they're not out of the running either. They're 5-1 in the ACC and a win against Tech would move them into at least second in the ACC, but they have to play Miami next week, so even a win this week doesn't guarantee them making the championship, let alone the CFP.
The BetQL computer model has the Yellow Jackets winning in 53% of it's simulations with a projected final score of 31-30. Our tip: take Georgia Tech's moneyline on FanDuel currently at -128.
Check out our full game analysis here.
It seems like a broken record, but BYU basically needs to win out to make the CFP. A win against Cincinnati should be enough for them to make the Big 12 title game against Texas Tech, but they'd need to win that as well to guarantee their spot. Tech is the only team in the Big 12 currently in the projected CFP bracket so BYU would need to hope for a lot of upset losses to improve their ranking before taking a second loss this season to the Red Raiders. The Bearcats are also somehow not out of the picture, but need a miracle just to make the Big 12 title game. Any loss between now and the end of the season would close the book on Cincinnati's CFP hopes.
The BetQL computer model has the Cougars as 9 point favorites winning in 71% of its simulations. Our tip: Take BYU -2.5 from ESPNBET currently at -115.
Check out our full game breakdown here
Matin Abrahams - Nov 19, 2025, 3:49am EST